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How to Make Homemade Disinfect Wipes (Like Lysol Wipes)

Mary Beth
Homemade DIY disinfecting wipes made with two ingredients and optional essentials oils. Made using CDC recommendations. Similar to Lysol and Clorox Wipes.
5 from 3 votes
Active Time 5 mins
Active Time 5 mins
Total Time 10 mins

Tools and Equipment

Paper Towel Roll – I used a 150 Sheet Roll with the select and tear option so that the wipes are smaller and more like store-bought wipes
Alcohol – you absolutely must use alcohol that is at least 60% alcohol. I used 91% rubbing alcohol for this recipe
Hydrogen Peroxide – “is active against a wide range of microorganisms, including bacteria, yeasts, fungi, viruses, and spores 78, 654.” (per the CDC)
Distilled Water
Essential Oils – not necessary but they do give it a nice scent. I used Thieves because I had it on hand but you can use a multitude of other oils including tea tree, lavender, peppermint, rosemary, eucalyptus, lemon, and cinnamon.


  • Alcohol – 14 ounces
  • Hydrogen Peroxide – 2 Tablespoons
  • Distilled Water – 2 ounces
  • Essential Oils – 30 to 45 drops


  • Choose a container with a lid to hold the wipes. You can use a glass container as I did, or an old plastic coffee can or any other large container with a lid. Wash and dry the container thoroughly first.
  • Cut the paper towel roll in half. You will need a large sharp knife for this. Do not use a serrated knife or you will have a paper mess! I used a knife from this set, which I love and highly recommend. It’s a great deal for the price.
  • Place paper towel roll in the container.
  • Add all liquid ingredients in measuring cup and mix well.
  • Slowly pour mixture over paper towels.
  • Place lid on the container and allow the paper towels to absorb the mixture. Pull out the cardboard tube.
  • For use, pull the towels out from the center of the roll. It works like magic and the wipes will come out and up one at a time.


I wipe down my countertops, faucets, doorknobs, toilet handle, light switches, smartphone, remote controls, keyboard, mouse, etc. often throughout the day.
You can check out my list of  25 Things to Disinfect Here for more ideas of items in and out of your home (like your car!) to wipe down.
Keyword DIY disinfectant wipes, homemade disinfectant wipes, homemade Lysol Wipes
Tried this DIY? Let me know what you think!Mention @TheHowToHome or tag #thehowtohome!
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